MicroRNAs and Hypertension

(Review article)

  • Nikolina Kolobarić Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Scientific Center of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, Croatia http://orcid.org/0000-0002-5649-8317
  • Ines Drenjančević* Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Scientific Center of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, Croatia http://orcid.org/0000-0003-4964-7721

Abstract

MicroRNAs (miRNAs) are non-coding, highly conserved RNAs found in all biological fluids, that are emerging as master regulators of gene expression, consequently impacting a variety of biological processes in both healthy and diseased environments. There are still certain limitations regarding analysis of circulating miRNAs, specifically concerning standardisation and accuracy of obtained data. However, there is an indisputable therapeutic and diagnostic potential, confirmed by recent research. Hypertension, as one of the leading causes of death in modern world, has been in the focus of scientific society for several decades now. So, it is of outmost importance to investigate and pinpoint appropriate miRNAs for early indication and diagnosis of hypertension in general population. More in vivo and clinical research is necessary in animal and human models in order to exploit the full potential of this novel technology.

Published
Apr 27, 2022
How to Cite
KOLOBARIĆ, Nikolina; DRENJANČEVIĆ*, Ines. MicroRNAs and Hypertension. Southeastern European Medical Journal, [S.l.], v. 6, n. 1, p. 53-67, apr. 2022. ISSN 2459-9484. Available at: <http://seemedj.mefos.unios.hr/index.php/seemedj/article/view/244>. Date accessed: 03 july 2022. doi: http://dx.doi.org/10.26332/seemedj.v6i1.244.
Section
Articles