Optical Coherence Tomography Angiography:

Dunja Bajtl; Mirjana Bjeloš*; Mladen Bušić; Benedict Rak; Ana Križanović; Biljana Kuzmanović Elabjer

doi:10.26332/seemedj.v3i2.107

Dunja Bajtl Department of Ophthalmology, University Hospital Centre Osijek, Osijek, Croatia
Mirjana Bjeloš* Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Ophthalmology, University Hospital “Sveti Duh”, Zagreb, Croatia; Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Mladen Bušić Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Ophthalmology, University Hospital “Sveti Duh”, Zagreb, Croatia; Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia
Benedict Rak Department of Ophthalmology, University Hospital “Sveti Duh”, Zagreb, Croatia
Ana Križanović Department of Ophthalmology, University Hospital “Sveti Duh”, Zagreb, Croatia
Biljana Kuzmanović Elabjer Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Ophthalmology, University Hospital “Sveti Duh”, Zagreb, Croatia; Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia

DOI: https://doi.org/10.26332/seemedj.v3i2.107

Abstract

Optical coherence tomography angiography (OCT-A) is a new non-invasive technology for imaging of retinal and choroidal vasculature of the macular area with resolution comparable to histological sections. OCT-A does not require usage of intravenous dye, contrary to fluorescein angiography, the current gold standard for imaging of retinal vessels, and indocyanine-green angiography, which is important for imaging of choroidal vessels. With the advancements in optical coherence tomography (OCT) scanning speeds and creation of powerful algorithms for improvement of image quality in recent years, OCT-A imaging of macular vasculature, superficial, deep and avascular retinal complex, as well as choriocapillaris and deep choroid has become available in everyday clinical practice. This review covers aspects important for understanding choroidal and retinal blood supply, as well as the development, mechanisms and clinical application of OCT and OCT-A technology.

(Bajtl D, Bjeloš M, Bušić M, Rak B, Križanović A, Kuzmanović Elabjer B. Optical Coherence Tomography Angiography – A New Insight Into Macular Vasculature. SEEMEDJ 2019; 3(2); 63-75)

Keywords: angiography, optical coherence tomography, vasculogenesis, angiogenesis, fovea centralis